Method of producing narcotica



Patented 'Dec. 18', 1928.

UNITED. STATES PATENT OFFICE.

Enron nnssn, 013mm], enananmlssxenon To run Fran eann a co. A.-G., or

mmsnnn, GERMANY.

'mn'rnonor raonucme NABGOTICA.

' No Drawing: Application filed November 17, 1927, Serial No. 234,039, and in Germany March 10,1921.

Inorder to create a local narcosis or anaesthesia cocaine was hitherto used in solutions of rather high concentration. The use of co-. caineis therefore very dangerous in cases a in which there is any possibility that the substance may reach the-circulat1on of matter. When cocaine is for creating a local narcosis it is therefore very difficult to prevent more or less serious poisonin s of the organism.

I have however now ound that when cocaine or salts of cocaine are mixed with adonidine then; products will be formed which with respect to their narcotising ef- .-i:'ects by farsurpass the cocaine. The new F products will even at 5 of the usual concentration give the sameeflect as or even a better efiect than cocalne alone.

When producing (the new remedy) in practise the cocaine or the salts of cocaine are treated with a quantity ofadonidine amounting maximally to 100 per cent of the cocaine to be treated.

When working in accordance with the above mentioned method a concentration of 5% will yield the same efiectas the cocaine solutions of'the highest concentration. The

adonidine is employed in quantities amounting to 0,52%. The special technical efiects obtained are these, that cocaine is saved and that the poisonous efiects of both ingredients are considerably reduced.

' A 'further advantageis this that the misuse of cocaine will decrease, since the poisonous eflect of the same is considerably re-. duced.

I claim:

' 1. A method of producing anaesthetic remedies, consisting in treating cocaine-containing substances with adonidine.

2. A method of producing anaesthetic remo edies, consistingin treating salts of cocaine with adonidine.

3. A method of producing anaesthetic remedies, consisting in treating cocaine with adonidine.

4.A method of producing anaesthetic remedies, consisting in treating cocaine with an amount of adonidine not surpassing 100 per cent of the cocaine.

5. As a commercial product, an anaesthetic remedy containing cocaine and adonidine. DR. ERICH HESSE. 

